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A. Glycogen (n residues) + Pi - - > glucose-1-phosphate + glycogen (n-1 residues) B. Glycogen (n residues) + 3 ADP + 3 Pi +2 NAD(+) - - > 2 pyruvate + glycogen (n-1 residues) + 3 ATP + 2 NADH + 2 H(+) + 2 H2O Answered - [the liver by phosphorolysis] [the muscles by phosphorolysis] [the muscles by hydrolysis] [Both (a) and (b)] are the options of mcq question Glucose from the breakdown of glycogen is obtained in realted topics topics with 0 Attempts, 0 % Average Score, 0 Topic Tagged and 0 People Bookmarked this question which was asked on Nov 26, 2018 00:34
The regulation of glycogen metabolism is a major therapeutic strategy for blood glucose control in type 2 diabetes.

Activation of glycogen phosphorylase and phosphorolysis of glycogen: The active form of glycogen phosphorylase kinase phosphorylates and activates glycogen phosphorylase.Active Inhibitor 1 protein and direct phosphorylation by cAMP-dependent protein kinase keep protein phosphatase 1 in the inactive state … Reciprocal Hormonal Regulation of Glycogen Synthesis and Degradation. 49 Glycogen phosphorylase catalyzes the reaction in which an (α1→4) glycosidic linkage joining two glucose residues in glycogen undergoes attack by inorganic phosphate, removing the terminal glucose residue as α-D--glucose-1-phosphate (Fig. In this case, the use of phosphorolysis instead of hydrolysis bypasses the hexokinase reaction, thereby saving one equivalent of ATP. This phosphorolysis reaction is catalyzed by a pyridoxal-5-phosphate requiring enzyme Glycogen phosphorylase. Bond cleavage is by substitution of a phosphoryl group (phosphorolysis). glycogen (n) + Pi glycogen (n-1) + glucose-1-Pglycogen (n) + Pi glycogen (n-1) + glucose-1-P The two types of PhK deficiency are liver PhK deficiency (characterized by early childhood onset of hepatomegaly and growth restriction, and often, but not always, fasting …

Glycogen phosphorylase catalyses phosphorolysis of glycogen to within 4 residues of a branch point and then stops. The reaction occurs with acid/base assistance from a suitably positioned carboxylate residue. What is the overall or net reaction for the conversion of this unit into 2 pyruvate, starting with phosphorolysis of the glucose unit? Glycogen phosphorylase can only carry out the glycogen breakdown process by itself until a limited extent before encountering an obstacle. Glycogen phosphorolysis can form a metabolic shuttle to support Ca2+ uptake by sarcoplasmic reticulum membranes in skeletal muscle.

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