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Entrez Gene Summary for MAPK1 Gene This gene encodes a member of the MAP kinase family.

ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. The protein encoded by the MAPK3 gene is a member of the MAP kinase family. Taken together, ERK1/2 plays a significant role in mediating LH surge-induced gene expression in granulosa and theca cells of the ovulating follicle in cattle.

Phosphorylation of ERKs leads to the activation of their kinase activity. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. They are expressed in all tissues, at varying levels. Mitogen-activated protein kinase 1 (MAPK1) is also known as "extracellular signal-regulated kinase 2" (ERK2). (2011) cloned human FAM129B. Charest et al. Involved in central nervous system development; chordate embryonic development; and eye development. To search for shRNA targets, enter the gene name, symbol, alternate symbol, homologs, accession number, RefSeq, TRC number or gene ID number in the search box and look for shRNA links in the results. They referred to the protein as p44(erk1) and the gene as ERK1. Other names include: Mitogen-activated protein kinase 3; MAP kinase 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-MAPK3; PRKM3. They were found during a search for protein kinases that are rapidly phosphorylated after activation of cell surface tyrosine kinases such as the epidermal growth factor receptor.

Two similar (85% sequence identity) protein kinases were originally called ERK1 and ERK2.

(1993) cloned a cDNA encoding a member of a family of tyrosyl-phosphorylated and mitogen-activated protein kinases (MAPKs) that participates in cell cycle progression. Gene Type: protein_coding_gene: Location: Chr: 3 Mapping Details/Browsers Description: Predicted to have MAP kinase activity.

Model STJ97782 Host Mouse Reactivity Human, Mouse, Rat Applications IHC Immunogen Recombinant peptide derived from ERK1 Gene ID 5595 Gene Symbol MAPK3 Dilution range IHC 1:100-200 Specificity ERK1 Mouse Monoclonal Antibody (4G11) detects endogenous levels of MAPK3

Complete information for AKT1 gene (Protein Coding), AKT Serine/Threonine Kinase 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene … ERK1 and ERK2 (MAPK3 and MAPK1) transduce signals from growth factors and phorbol esters. There are 2 ERK1/MAPK3 antibody for WB, 1 ERK1/MAPK3 antibody for ICC/IF, 2 ERK1/MAPK3 antibody for IP, 1 ERK1/MAPK3 antibody for IHC-P. ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. The deduced 746-amino acid protein has a calculated molecular mass of 83 kD.

ERK Extracellular signal-regulated kinases are a group of mitogen-activated protein kinases (MAPK) that mediate intracellular signaling.

MAPK3, also known as ERK1, is part of the Ras-Raf-ERK signal transduction cascade and is involved in cell growth, differentiation, apoptosis, and transformation in response to extracellular signals in most tissues. All the ERK1/MAPK3 anbodies are produced in … Genes with the red cube "validated" symbol designate validated clones that have been shown to have knockdown efficiencies of 70% or greater at the mRNA level in one or more cell lines.

The cDNA encodes a 379-amino acid polypeptide sharing approximately 96% predicted amino acid identity with partial sequences of rodent erk1 cognates.

It contains an N-terminal pleckstrin (PLEK; 173570) homology (PH) domain, a C-terminal proline-rich domain, and 6 potential serine phosphorylation sites.In growing HeLa cells and mouse embryonic fibroblasts, FAM129B localized to the cytoplasmic compartment. Anti-ERK1 antibody Description Mouse monoclonal to ERK1.

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